Occurrence frequency of renal replacement therapy (RRT) in diabetic patients compared with non-diabetic patients in Germany during 2002-2008

Occurrence frequency of renal replacement therapy (RRT) in diabetic patients compared with non-diabetic patients in Germany during 2002-2008

Andrea Icks, Burkhard Haastert, Jutta Genz, Guido Giani, Falk Hoffmann, Rudolf Trapp, Michael Koch

Summary

This study was conducted to determine the number of people with and without diabetes receiving renal replacement therapy in the Germany.

Methods

Using data from a regional dialysis center (population of 310,000), all new patients aged 30 and over admitted to the RRT between 2002 and 2008 were enumerated.

Results

49.6% of all patients (N=544) provided RRT had diabetes. 58% were men, the average age was 70.3 (11.4 years). The occurrence frequency of RRT among patients with and without diabetes per 100,000 people (standardized to the 2004 German population) was 213.7 [ 95% CI), 159.5– 267.8] and 26.9 (95% CI, 22.5– 31.3) [ men] and 130.2 (95% CI, 65.6-194.9) and 16.4 (95% CI 13.5- 19.3) [women]. The standardized relative risk was 7.9 (5.9-10.8) for men and 8.0 (4.7-13.5) for women. A significant mutual influence between age and diabetes was determined, the relative risk was lower in older patients. Among those with diabetes, the corresponding risks were 0.87 for men and women, and 0.41 and 0.35 for men and women in the general population.

Final result

In this demographic study conducted in Germany, it was found that older people with diabetes request for RRT 8 times more than patients without diabetes. Elevated risk for RRT may be associated with diabetes in diabetic patients as well as in the general population.